£20,000 invested in AstraZeneca shares 5 years ago is now worth…

AstraZeneca (LSE: AZN) shares have benefited from one of the most impressive longâterm reinventions in the FTSE 100.
A decade ago, it was a lumbering, patentâcliffâridden pharma giant. Today it is a highâgrowth, oncologyâdriven, researchâled machine with global scale and a pipeline that most rivals would kill for.
And from 8 April 2021 to now, a £20,000 holding in the stock would have grown into£44,108 once dividends are included. That is a share price gain of £21,143, plus another £2,965 in dividends, giving a total return of around 121%.
That said, I believe there is still a huge gap remaining between the stockâs price and its âfair valueâ. And experience has shown that share prices tend to converge to this fair value over time.
So, what sort of potential price gains are we looking at?
Strong growth momentum
A risk to AstraZeneca is any delay in the rampâup of key oncology launches that could squeeze its earnings. And it is ultimately growth in these that power any firmâs share price higher. Another is any regulatory or clinical setbacks across its lateâstage pipeline that could delay key productsâ path to market.
However, analysts forecast that the companyâs earnings will grow a very robust 13% a year over the medium term. And these projections look well supported by recent results.
Reported earnings per share (EPS) soared 45% year on year to $6.60 (£5), reflecting strong operating leverage and lower impairment charges. Revenue jumped 9%to $58.7bn, driven by Oncology, Cardiovascular, Renal & Metabolism, Respiratory & Immunology, and Rare Disease. And operating profit rose 9% to $18.49bn, powered by strong performances from Tagrisso, Imfinzi, Calquence and the accelerating antibody-drug cancer medicines portfolio.
Looking ahead, management expects midâtoâhigh singleâdigit revenue growth and low doubleâdigit core EPS growth in 2026. AstraZeneca also reiterated its forecast that it will hit its 2030 target of $80bn in annual revenue.
Where âshouldâ the shares be trading?
In my experience as a former investment bank trader, discounted cash flow (DCF) analysis is the optimal way to ascertain a shareâs fair value.
It does this by projecting an underlying businessâs future cash flows and then âdiscountingâ them back to today. The more uncertain those earnings are, the higher the return investors demand and the greater the discount applied.
Some analystsâ DCF modelling is more bearish than mine due to the inputs used. However, based on my DCF assumptions â including a 7.2% discount rate â AstraZeneca shares are 38% undervalued at their current £149.07 price.
Therefore, their fair value could secretly be close to £240.44 a share.
And because stocks can trade to their fair value over time, this price-to-value gap suggests a potentially terrific buying opportunity to consider today if those DCF assumptions hold.
My investment view
I believe the market is still underestimating AstraZenecaâs earnings power, driven by the rapid shift into a higherâgrowth, innovationâled business.
With analysts expecting doubleâdigit profit growth and management guiding to sustained expansion through to 2030, it looks much stronger than the share price implies.
So, I will be adding to my holding in the firm shortly and think it worthy of other investorsâ attention.
I also have my eye on other high-growth stocks that look seriously undervalued.
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Simon Watkins has positions in AstraZeneca Plc. The Motley Fool UK has recommended AstraZeneca Plc. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.
